SpermFilter®
Application
SpermFilter® is a silane-silica based density gradient medium used in ART for separation and purification of highly motile human spermatozoa.
Composition
SpermFilter® is composed of silica particles covalently coated with silane and resuspended in isotonic phosphate and Hepes buffered saline.
Quality Control
- pH: 7.4 ± 0.2
- Osmolality: 300 ± 10 mOsm/kg
- Endotoxin: < 0.1 ng/ml (<1 EU/ml)
- Sterility: SAL 10-3
- Sperm Motility Test
Shelf Life
Two years from production date when stored refrigerated (2° - 8º C). After opening, use aseptic working procedures. Avoid freezing.
Sterility
The medium is sterilized by filtration and sterility is ensured by testing each batch. Sterility tests verify the absence of viable micro-organism (bacteria, yeast and fungi).
Packages
SpermFilter® is supplied in pharmaceutical grade borosilicate glass bottles with Teflon-coated rubber stoppers and tamper proof seals.
Clinical Performance
SpermFilter® and PureSperm® have been tested in a comparative study of 898 ART cycles (245 IUI-H, 58 IUI-D and 595 IVF/ICSI cycles). There was no significant difference.Source: Acta Obstetricia et Gynecologica Scandinavica Vol. 82 Issue 10 Page 929 October 2003 (Adobe PDF format).
Ready-to-use gradients 40% and 80%
SpermFilter® ready-to-use gradients are diluted with SpermWash® (Hepes buffered isotonic medium with Gentamicin). Shelf life gradients: 18 months from production date. Store refrigerated at 2° - 8º C. Avoid freezing and exposure to light.
Product Information (Adobe PDF format)
Questions and Answers
Download Certificate of analysis